Monday, April 20, 2015

about Naringin


Naringin is a flavanone-7-O-glycoside between the flavanone Naringenin and the disaccharide neohesperidose. The flavonoids naringenin and hesperetin, which form the aglycones of naringin and hesperidin, occur naturally in citrus fruits, especially in grapefruit, where naringin is responsible for the fruit's bitter taste. In commercial grapefruit juice production, the enzyme naringinase can be used to remove the bitterness created by naringin. In humans the naringin is metabolized to the flavanone naringenin.
The chemical formula of the compound is C27H32O14. It has a molecular weight of 580.53 and in its purest form, the compound appears as a yellow powder. Chemically, it is a conjugate of a sugar molecule and naringenin, which is another flavonoid present in grapefruit.
Generally, flavonoids protect cells from molecules that contain reactive oxygen atoms, commonly called free radicals. Usually, flavonoids reduce the damaging effects of free radicals by stimulating the production of glutathione, which is a strong anti-oxidant. Flavonoids can also increase the effectiveness of vitamin C as an anti-oxidant. In addition, flavonoids play a role in inflammation control by moderating certain cells of the immune system. They can also inhibit the activity of certain types of viruses, including the herpes simplex virus.
from:Natural standard substance

Thursday, April 16, 2015

Introduction of Geniposide


Geniposide is an iridoid glycoside with a variety of biological activities including neuroprotective, anti-diabetic, antiproliferative, and antioxidative activity. Geniposide has been shown to regulate Nrf2 translocation and upregulate downstream antioxidant protein HO-1 expression through the PI3K/Akt signaling pathway, which may account for its neuroprotective and antioxidative activity. Glucagon-like peptide 1 (GLP-1) receptor may also play a critical role in geniposide induced HO-1 expression.
CAS : 24512-63-8
Molecular Formula : C17H24O10
Formula Weight : 388.37
Description :
Geniposide   has been reported to have a hypoglycemic effect.
Source: the fruit of Gardenia jasminoides
Appearance:little yellow crystal.
from:Acridine Raw Material

Monday, April 13, 2015

Cyclovirobuxine D is an anti-atrial fibrillating agent


C26H46N2O, or also known as cyclovirobuxine D, has for the first time been isolated from Buxus papilosa. It has a steroid nucleus in trans/cis/trans configuration. Two of the three cyclohexane rings adopt half-chair conformations and the third ring, with an equatorially attached methylamino substituent, is in a chair conformation. The cyclopentane ring has a half-chair conformation and the N-methylaminoethane group is equatorially attached to it. N-HO and C-HN interactions are observed in the molecular structure and the crystal structure is stabilized by van der Waals interactions
Cyclovirobuxine D is an active compound extracted from Buxus microphylla, which has been used for treating acute myocardial ischemia in China.It significantly reduced the infarct size induced by ligating the coronary artery in rats, and the effect was almost abolished by glibenclamide, a blocker of ATP sensitive potassium channel, but it was not influenced by cyclooxygenase-2 inhibitor celecoxib or estrogen receptor antagonist tamoxifen.
from:Natural standard substance

Thursday, April 9, 2015

Introduction of Murrayone


Name : Murrayone
CAS : 19668-69-0
Molecular Formula : C15H14O4
Formula Weight : 258.27
Description :
Murrayone  inhibit tumor cell growth  and subcutaneous tumor growth in animals.So it can be used for preparation of anticancer drug.
from:Natural standard substance

Sunday, March 29, 2015

what is the role of Snake bile Extract?


Snake bile is the traditional Chinese medicine and precious natural medicinal material; It has very good medical healthcare value. It historically is rare Chinese traditional medicine. Compendium of Materia Medica think: Snake gale has the gas line, search the wind to wet phlegm, clear liver bright eye, in addition to poison the function of removing pathogens.
performance: this product according to Chinese traditional Chinese medicine theory and a long traditional folk secret recipe. Traditional Chinese medicine theory, inheritance of homologous food quality choose state ministry of food and medicine of Chinese medicinal materials general approval, fresh and high quality green tea, the snake gale science blends, the application of advanced production technology and equipment and refined taste, pleasant, natural is clear, the aftertaste letting a person is sweet, and fully experience the balance of the heart and cheerful. No matter of men, women and children all can drink, is the natural taste GanXiang care treasures.
Main function:detoxification, benefit liver and bright eye, better one's looks.
applicable people :
A use eye fatigue and the fire within, icaligation
B sore throat, chronic angina, bronchitis, rhinitis, the asthma;
C organs disorders caused by imbalance of Yin and Yang, the itchy skin, facial blain rash, acne patients;
D Sub-healthy people and Three high-population
from:Natural standard substance

Wednesday, March 25, 2015

about Fimbriate Orostachys Extract


Name:Fimbriate Orostachys Extract
 Description:
Constituents: Containing flavonoids, quercetin, kaempferol, oxalate,etc.
Actions:Isopropylidene redoheptuloride is effective against BEL7402 and MGC803 cell lines. The inhibiting rate of water and alcohol extrct of Orostachys fimbriainst on S180 was 36.4% and 25.4% respectively. The 50% alcohol and 75% alcohol extract of Orostachys fimbriatus obtained AC.AC had inhibiting action on S180, the inhibitory rate was 31%~37.9%.
Indications: For cervical carcinoma.
from:Natural standard substance

Monday, March 23, 2015

about Manyprickle Acathopanax Root Extract


Name: Manyprickle Acathopanax Root  Extract
Description: Modern medicine study indicates Manyprickle Acathopanax Root can boost up hominine immunity,improve prevent disease’s ability,bring effects to systema nervorum centrale,help sleep, adjust pituitary--suprarenal cortex function,heighten demic ability to prevent stressif there is enough combustion of oxygen in the body and boost metabolism.it will keep the skin elastic and beautiful,in addition Manyprickle Acathopanax Root can stimulate male hormone,so it is an healing healthcare medicine.
from:Natural standard substance